Dihydrotestosterone (DHT) treatment over two years does not halt prostate growth, according to study findings published in the Annals of Internal Medicine (2010;153:621-632).

In the study, 114 men aged 50 years and older with no known prostate disease received the hormone therapy or placebo for 24 months to determine whether long-term administration of a nonamplifiable pure androgen would reduce prostate growth.

Average prostate size increased over time in all men, with total prostate volume growing by 29% and central prostate volume by 75%, accompanied by a 15% hike in serum PSA level.

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