Allopurinol use is associated witha decreased risk of being diagnosedwith benign prostatic hyperplasia (BPH),researchers reported online in ProstateCancer and Prostatic Diseases.

In a study of 74,754 men, VilleKukko, of the University of Tamperein Finland, and colleagues found thatmen using allopurinol had a 22%lower risk of a BPH diagnosis and a19% and 33% decreased likelihood ofBPH medication use and BPH-relatedsurgery, respectively, after multivariableadjustment. The investigatorsobserved that only body mass index(BMI) modified the risk association,with decreased risks found onlyamong men with a BMI above themedian (27.3 kg/m2).

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