A walnut-enriched diet reduced the establishment and growth of human prostate cancer in mice.
In a study, prostate tumors developed in three of 16 immune-deficient mice (18%) given the walnut-enriched diet compared with 14 of 32 immune-deficient mice (44%) that were being fed a standard mouse diet.
The first palpable tumors appeared three to four weeks after xenograft implantation, and were first detected in the walnut-eating mice.
However, the tumors in the walnut-fed mice grew more slowly, with the final average tumor size approximately one-fourth smaller in those animals than in the controls.
As Russel J. Reiter, PhD, and collaborators noted in Cancer Investigation (2013;31:365-373), previous research had shown that a standard mouse diet enriched with walnuts restrained the growth of human breast cancer cells, and dietary walnut supplementation improved biomarkers of prostate and vascular health in men aged 45 to 75 years.