High serum levels of vitamin D may have a protective effect against bladder cancer, according to a recent systematic review and meta-analysis published online ahead of print in Tumor Biology.

The meta-analysis, by Yong Liao, MD, and colleagues at Sichuan Academy of Medical Sciences & Sichuan Provincial People’s Hospital in Chengdu, China, included 89,610 participants and 2,238 bladder cancer cases.

A high serum level of 25-hydroxyvitamin D was associated with a significant 25% decreased relative risk of bladder cancer, the researchers reported. 

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