A previously described beneficial relation between rye intake and prostate cancer (PCa) may be at least partly explained by the results of a small, randomized controlled trial of 17 men with low-risk PCa who had chosen not to undergo surgery, radiation, or chemotherapy.

After replacing all cereal grain products with whole-grain rye and rye bran products for six weeks, some men exhibited a decrease in the obesity hormone leptin, significantly lowered homocysteine, and a small but significant weight loss, according to a report in The Journal of Nutrition 2011;141:2126-2132).