Prostate volume in men with benign prostatic hyperplasia has little effect on the safety and efficacy of GreenLight HPS laser photoselective vaporization prostatectomy (PVP), researchers reported in the Journal of Endourology (online ahead of print). Xiao Gu, MD, PhD, of the University of Oklahoma Health Sciences Center in Oklahoma City, and colleagues based that conclusion on a study of 207 men undergoing PVP.
The researchers stratified the men into two groups based on prostate volume: 80 mL or greater (57 patients) or less than 80 mL (150 patients).
Clinical outcomes (American Urological Association Symptom Score, Quality of Life score, maximum flow rate, and post-void residual volume) showed immediate and stable improvement from baseline in each group, and investigators observed no significant differences between the groups during follow-up. The incidence of adverse events was low and similar in both groups.