Prostate cancer (PCa) is more likely to be diagnosed in men who have been hospitalized for clinical benign prostatic hyperplasia (BPH) or undergone surgery for the condition, according to a Danish study.

The study of more than three million men—the entire male population of Denmark—found that men hospitalized and operated on for clinical BPH had a two- and three higher incidence of PCa, respectively, and a twofold and almost eightfold increased risk of dying from PCa compared with general population controls, investigators reported in European Urology (2011;60:691-698). The authors cautioned that their findings should not be used to infer causality.