Percutaneous nephrolithotomy (PCNL) is associated with an increased risk of diabetes mellitus, according to a study.

A team led by Herng-Ching Lin, PhD, of Taipei Medical University in Taiwan, studied 3,344 patients with nephrolithiasis and compared the 304 patients who underwent PCNL with the 3,040 did not. During a five-year follow-up period, the PCNL-treated patients had a nearly twofold increased risk of being diagnosed with diabetes mellitus compared with the non-PCNL group after adjusting for confounders, the researchers reported online ahead of print in the International Journal of Urology.

In addition, PCNL was associated with a 79% and 71% increased risk of a diabetes mellitus diagnosis compared with extracorporeal shockwave lithotripsy and endoscopic intervention, respectively.

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