Living kidney donors are at no higher risk for requiring acute dialysis than non-donors, according to a study conducted in Canada and the United States.
Investigators led by Amit X. Garg, MD, of the University of Western Ontario in London, compared 2,027 living kidney donors with 20,270 matched non-donors. After a median follow-up period of 6.6 years, only one donor received acute dialysis, which translated into 6.5 events per 100,000 person-years, according to an online report in Nephrology Dialysis Transplantation. This rate was no different statistically from the non-donor group, in which 14 subjects required acute dialysis, for a rate of 9.4 events per 100,000 person-years.
“The overall incidence of acute dialysis is very small and will not occur in over 99.99% of donors in the decade following donation,” the investigators wrote “During this time, living kidney donors are unlikely to suffer from the inciting events that may pre-dispose to acute kidney injury.”
The authors added that when such events occur, “it is possible that the remaining kidney adequately compensates to prevent acute kidney injury.”