Stroke risk increases linearly withdecreasing glomerular filtration rate(GFR) and increasing albuminuria,according to a systematic reviewand meta-analysis published onlineahead of print in Nephrology DialysisTransplantation.

Stroke risk increased by 7% witheach 10 mL/min/1.73 m2 decreasein GFR and by 10% with each 25 mg/mmol increase in albumin-creatinineratio, researchers led by PhilipMasson, MD, of the University ofSydney in Australia, reported. Resultsdid not differ by stroke subtype, sex,and varying prevalence of cardiovascular risk factors

The systemic review and meta-analysisincluded 63 cohort studies witha total of 2,085,225 participants and20 randomized clinical trials with atotal of 168,516 participants.

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