Microwave ablation (MWA) shows potential as an alternative to parathyroidectomy for secondary hyperparathyroidism (SHPT), according to a new study published in Hemodialysis International.
Binghu Jiang, MD, of Nanchong Central Hospital, The Second Clinical Medical College, North Sichuan Medical College, Nanchong, China, and colleagues compared the different procedures in 81 SHPT patients who were on maintenance hemodialysis. The MWA and parathyroidectomy groups had 33 and 48 patients, respectively. The groups had no significant differences in baseline characteristics, according to the investigators.
The rates of achieving the recommended target for intact parathyroid hormone (iPTH) levels were significantly higher in the MWA group than in the parathyroidectomy group (57.58% vs 12.50%) at 1 day post-procedure, 45.45% vs 16.67% at 1 week, and 57.58% vs 16.67% at 2 weeks, 57.58% vs 22.92% at 1 month, 69.70% vs 35.42% at 3 months, 76.47% vs 28.57% at 6 months, 87.50% vs 47.37% at 12 months, and 81.82% vs 52.63% at 24 months.
Baseline predictors of response to MWA included patient age and baseline iPTH.
Jiang B, Wang X, Yao Z, et al. Microwave ablation vs. parathyroidectomy for secondary hyperparathyroidism in maintenance hemodialysis patients. Hemodial Int. 2019; published online ahead of print.