Secondary Hyperparathyroidism

Microwave Ablation for SHPT May Offer Alternative to Parathyroidectomy

Publish Date March 7, 2019

In a small study of hemodialysis patients with secondary hyperparathyroidism, microwave ablation achieved higher rates of the recommended target levels of intact parathyroid hormone.

SGLT2 Inhibitor Increases Serum Phosphate, PTH, and FGF23

Publish Date February 5, 2019

Study supports the hypothesis that altered tubular phosphate handling drives the increase in serum phosphate during SGLT2 inhibition.

Genetic Variant in FGF23 Tied With Cardiovascular Risks in HD

Publish Date February 1, 2019

In a study, having the single nucleotide polymorphism rs11063112 in fibroblast growth factor 23 was associated with a 32% greater risk for cardiovascular mortality.

Active Vitamin D Therapy Prolongs Survival in Hemodialysis

Publish Date January 29, 2019

In a study of hemodialysis patients, vitamin D users had a lower mortality rate than nonusers: 9 vs 13 per 100 person-years.

Effect of Payment Bundling on Calcimimetic Use Still Unclear

Publish Date January 24, 2019

Younger age, longer dialysis vintage, and black race are associated with greater cinacalcet prescribing in the United States.

Parathyroidectomy-Associated Hyperkalemia Common in HD Patients

Publish Date January 22, 2019

Hyperkalemia developed in nearly 67% of hemodialysis patients during or immediately following total parathyroidectomy with autotransplantation for secondary hyperparathyroidism.

Cinacalcet Appears Safe, Effective for Children With SHPT

Publish Date January 9, 2019

In a small study, more than half of pediatric patients receiving cinacalcet experienced a 30% or greater decline in mean intact parathyroid hormone.

Cardiovascular Event Risk Higher With Total Parathyroidectomy

Publish Date January 7, 2019

Patients who underwent subtotal vs total parathyroidectomy had half the risk for cardiovascular events.

Parathyroidectomy for SHPT Reduces Aortic Calcification

Publish Date January 4, 2019

In a small study of hemodialysis patients with secondary hyperparathyroidism, abdominal aortic calcification decreased more in patients who underwent parathyroidectomy than in those in a control group over 1 year.

VDRAs Do Not Lower Cardiovascular Event Risk in HD

Publish Date December 11, 2018

Trial results do not support use of vitamin D receptor activators to prevent cardiovascular events in patients with end-stage renal disease and low intact parathyroid hormone levels.