Vitamin K Antagonists, Liver Dysfunction Implicated in Calciphylaxis
In a small study, vitamin K antagonist use and liver dysfunction emerged as the most important factors in the development of calciphylaxis.
Secondary Hyperparathyroidism
SECONDARY HYPERPARATHYROIDISM
Target Vitamin D Levels in CKD With SHPT May Need Updating
In an analysis of 2 randomized trials of patients with stage 3 to 4 chronic kidney disease, iPTH suppression did not occur until serum 25-hydroxyvitamin D rose to at least 50.8 ng/mL.
Post-Parathyroidectomy Hungry Bone Syndrome Less Problematic in PD
In a single center study, hungry bone syndrome developed in fewer patients on peritoneal dialysis than hemodialysis after parathyroidectomy.
Pretransplantation PTH May Influence the Risk for Tertiary HPT
In a study, patients with the highest preoperative levels of PTH tended to have higher postoperative levels than other transplant recipients.
SHPT Linked With Low Bone Density in CKD
In a study of patients with chronic kidney disease, secondary hyperparathyroidism was associated with high risk for reduced bone mineral density, particularly at the hip.
Microwave Ablation for SHPT May Offer Alternative to Parathyroidectomy
In a small study of hemodialysis patients with secondary hyperparathyroidism, microwave ablation achieved higher rates of the recommended target levels of intact parathyroid hormone.
SGLT2 Inhibitor Increases Serum Phosphate, PTH, and FGF23
Study supports the hypothesis that altered tubular phosphate handling drives the increase in serum phosphate during SGLT2 inhibition.
Genetic Variant in FGF23 Tied With Cardiovascular Risks in HD
In a study, having the single nucleotide polymorphism rs11063112 in fibroblast growth factor 23 was associated with a 32% greater risk for cardiovascular mortality.
Active Vitamin D Therapy Prolongs Survival in Hemodialysis
In a study of hemodialysis patients, vitamin D users had a lower mortality rate than nonusers: 9 vs 13 per 100 person-years.
Effect of Payment Bundling on Calcimimetic Use Still Unclear
Younger age, longer dialysis vintage, and black race are associated with greater cinacalcet prescribing in the United States.
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