Secondary Hyperparathyroidism

Study: Higher-Dose Dialysate Calcium Better for SHPT

Publish Date July 30, 2019

For patients on peritoneal dialysis, 1.75 vs 1.25 mmol/L dialysate calcium was superior at reducing intact parathyroid hormone levels, meta-analysis revealed.

Calcitriol Loading May Not Prevent Post-PTx Hungry Bone Syndrome

Publish Date July 29, 2019

In a small study, hungry bone syndrome developed in nearly 29% of patients despite receiving high-dose calcitriol prior to total parathyroidectomy with autotransplantation.

Holistic Approach to Managing SHPT Recommended for Older Adults

Publish Date July 29, 2019

A new review suggests transitioning from a disease-oriented approach to a patient-oriented approach for better risk-benefit balance.

Post-Parathyroidectomy Hungry Bone Syndrome Risk Factors ID’d

Publish Date July 18, 2019

Hungry bone syndrome developed in nearly 88% of patients following parathyroidectomy with autotransplantation for refractory secondary hyperthyroidism.

Parathyroid Hormone Predicts Fracture, Vascular Events, Death in CKD

Publish Date July 2, 2019

In a study of CKD patients, patients with baseline PTH levels of 0, 69, and 58 pg/mL had the lowest risks for fracture, vascular events, and death, respectively.

Preoperative Potassium Predicts Hyperkalemia Post-Parathyroidectomy

Publish Date July 1, 2019

In a study of hemodialysis patients, pre-operative potassium higher than 3.9 mmol/L correlated with greater risk for hyperkalemia after parathyroidectomy.

Vertebral Fracture Common in ESRD

Publish Date June 15, 2019

In a small study, 34% of dialysis patients had vertebral fractures, and patients in the highest tertile of parathyroid hormone level had a nearly 3-fold increased risk of these fractures compared with those in the middle tertile.

Higher Vitamin D Target May Be Needed to Manage SHPT

Publish Date June 15, 2019

New data support aggressive vitamin D repletion to a revised serum 25-hydroxyvitamin D target of at least 51 ng/mL in patients with chronic kidney disease.

Pre-Transplant Cinacalcet May Increase the Risk of Persistent SHPT

Publish Date June 5, 2019

Twice as many patients taking a high cinacalcet dose before transplantation required subsequent parathyroidectomy persistent secondary hyperparathyroidism.

Cinacalcet Frequently Discontinued, Reinitiated

Publish Date May 28, 2019

A European study of hemodialysis patients who were new users of cinacalcet found that the drug was discontinued in 35% of patients after 1 year.