Lower serum sodium levels in patients initiating peritoneal dialysis (PD) are associated with an increased risk of death, according to a new study published online ahead of print in Peritoneal Dialysis International.

Researchers led by Andrew Davenport, MD, of the Royal Free Hospital in Hampstead, U.K., studied 3108 PD patients enrolled at day 90 of renal replacement therapy into the U.K. Renal Registry database and who had sodium measurements available. After adjusting for covariates, patients in the lowest serum sodium group (137 mmol/L or less) had a 49% increased risk of dying compared with those who had the highest serum sodium levels (140 mmol/L or higher).

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