Lupus Nephritis Therapy Response Predicts Survival Odds
Complete response to induction therapy is associated with significant 82% decreased odds of death at 12 months.
Lupus Nephritis
LUPUS NEPHRITIS
Kidney Transplantation Ups Survival in Lupus Nephritis Cases
In a nationwide study, renal transplant recipients with lupus nephritis had a 70% lower risk for all-cause mortality than nonrecipients.
Urine Immunoassay Identifies Novel Lupus Nephritis Biomarkers
Using electrochemiluminescence, researchers found 5 urinary proteins that have “reasonable specificity” for lupus nephritis.
Similar Long-Term Outcomes in Early- vs Late-Onset Lupus Nephritis
Researchers observed comparable long-term outcomes between patients with late- and early-onset lupus nephritis.
SERPINA3 ID’d as Candidate Biomarker for Lupus Nephritis Activity
Researchers identified SERPINA3 as a potential urine biomarker to quantify lupus nephritis.
Tacrolimus Possibly Beneficial Long Term in Lupus Nephritis
Over a 5-year period, the drug was well tolerated and associated with significant declines in urinary protein-creatinine ratio and mean prednisolone dose.
Lupus Is a Leading Cause of Death in Young Women
Death from lupus ranked 10th in women 15 to 24 years, 14th in those aged 25 to 34 and 35 to 44 years.
Voclosporin Shows Promise as Lupus Nephritis Treatment
In a phase 2b trial, around half of patients taking the novel calcineurin inhibitor at a dose of 23.7 mg twice daily achieved complete remission at 48 weeks.
ESRD Risk Higher in SLE Patients Hospitalized for Infections
End-stage renal disease is 5-fold more likely to develop in patients with 3 or more infection-related hospitalizations versus none.
Sirukumab Ineffective in Lupus Nephritis
The primary outcome was reduction in proteinuria, as measured by protein-to-creatinine (P:C) ratio in a 12-hour urine collection, at 24 weeks compared with baseline.
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