Epidemiologic Study Compares SLE Manifestations in Different Racial Groups
Investigators examined racial/ethnic differences in manifestations of lupus and in the timing and risk of developing severe manifestations.
Lupus Nephritis
LUPUS NEPHRITIS
CDC: Racial Disparity Seen With Lupus-Related Deaths
Deaths among blacks occur sooner after diagnosis and at younger age compared with whites
Adverse Childhood Experiences Linked to Worse Lupus Outcomes
More adverse childhood experiences associated with depression, poor overall health for those with SLE
Elevated Fracture Risk Observed in SLE, Lupus Nephritis
Patients with systemic lupus erythematosus were at greater risk for fractures compared with controls.
Lupus Nephritis Therapy Response Predicts Survival Odds
Complete response to induction therapy is associated with significant 82% decreased odds of death at 12 months.
Kidney Transplantation Ups Survival in Lupus Nephritis Cases
In a nationwide study, renal transplant recipients with lupus nephritis had a 70% lower risk for all-cause mortality than nonrecipients.
Urine Immunoassay Identifies Novel Lupus Nephritis Biomarkers
Using electrochemiluminescence, researchers found 5 urinary proteins that have “reasonable specificity” for lupus nephritis.
Similar Long-Term Outcomes in Early- vs Late-Onset Lupus Nephritis
Researchers observed comparable long-term outcomes between patients with late- and early-onset lupus nephritis.
SERPINA3 ID’d as Candidate Biomarker for Lupus Nephritis Activity
Researchers identified SERPINA3 as a potential urine biomarker to quantify lupus nephritis.
Tacrolimus Possibly Beneficial Long Term in Lupus Nephritis
Over a 5-year period, the drug was well tolerated and associated with significant declines in urinary protein-creatinine ratio and mean prednisolone dose.
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