For Arthritis Awareness Month, Paul Hoover, MD, and colleagues provide insight into the research conducted by their team on understanding human lupus nephritis mechanisms using mouse models.
Exostosins are potential disease antigens, biomarkers, or both found in the glomerular basement membrane of some patients with lupus membranous nephropathy.
Most patients with lupus nephritis who flared after immunosuppressant discontinuation re-achieved remission after restarting immunosuppressive therapy.
Investigators stress the importance of smoking cessation in patients with systemic lupus erythematosus, particularly among those carrying particular risk alleles.
