Lupus Nephritis

Renal Arteriosclerosis Develops Prematurely in Lupus Nephritis

Publish Date January 13, 2020

A study found that renal arteriosclerosis develops 2 decades earlier in patients with lupus nephritis compared with healthy age-matched controls.

Belimumab Associated With Meaningful Improvement in Lupus Nephritis Trial

Publish Date December 25, 2019

GlaxoSmithKline announced positive results from the phase 3 BLISS-LN trial of belimumab for the treatment of active lupus nephritis in adult patients.

Itolizumab Receives Fast Track Status for Lupus Nephritis

Publish Date December 16, 2019

The FDA has granted Fast Track designation for itolizumab (EQ001; Equillium) for the treatment of lupus nephritis.

Voclosporin Superior to Standard of Care in Lupus Nephritis Trial

Publish Date December 12, 2019

Voclosporin was found to be superior to standard-of-care treatment in patients with lupus nephritis, according to data from the phase 3 AURORA trial.

Biopsy-Informed Management Safely, Accurately Predicts Flares in Lupus Nephritis

Publish Date September 13, 2019

This study reports the long-term renal outcomes of kidney biopsies performed at prespecified intervals to determine the safety and accuracy of tapering of maintenance immunosuppression.

Obinutuzumab Gets Breakthrough Status for Treatment of Lupus Nephritis

Publish Date September 19, 2019

The Food and Drug Administration (FDA) has granted Breakthrough Therapy designation to obinutuzumab (Genentech), a CD20-directed cytolytic antibody, for the treatment of adults with lupus nephritis. The designation was based on data from the phase 2 NOBILITY study that compared the efficacy and safety of obinutuzumab, in combination with mycophenolate mofetil (MMF) or mycophenolic acid…

Good Renal Transplant Outcomes Reported in Lupus Nephritis Cases

Publish Date August 23, 2019

In a small study, patients with lupus nephritis who underwent renal transplantation had 5-year graft and patient survival rates of 76.3% and 92.5%, respectively.

Epidemiologic Study Compares SLE Manifestations in Different Racial Groups

Publish Date June 6, 2019

Investigators examined racial/ethnic differences in manifestations of lupus and in the timing and risk of developing severe manifestations.

CDC: Racial Disparity Seen With Lupus-Related Deaths

Publish Date May 15, 2019

Deaths among blacks occur sooner after diagnosis and at younger age compared with whites

Adverse Childhood Experiences Linked to Worse Lupus Outcomes

Publish Date May 13, 2019

More adverse childhood experiences associated with depression, poor overall health for those with SLE