According to investigators, the existing NIH definition of interstitial inflammation in the kidneys of patients with lupus nephritis needs to be modified to account for inflammation in areas with and without fibrosis.
Patients receiving significant amount of immunosuppression prior to kidney transplantation should be counseled on these malignancy risks, according to investigators.
Early diagnosis and treatment of childhood-onset systemic lupus erythematosus is important to prevent lupus nephritis outcomes such as end-stage kidney disease.