Lupus Nephritis

Early Use of RAAS Inhibitors May Benefit Children With Lupus Nephritis

Publish Date June 24, 2022

Real-world data on use of RAAS inhibitors can be used to support future pragmatic studies to optimize management of childhood-onset SLE, according to investigators.

Lupus Nephritis Affects Health-Related Quality of Life

Publish Date June 15, 2022

Both renal and extra-renal manifestations of lupus nephritis need to be managed, according to investigators.

Second Biopsy Better Predicts ESKD in Lupus Nephritis

Publish Date June 2, 2022

A second biopsy adds valuable information on lupus nephritis course, according to investigators.

SLE Survival Rates Improving, But Lupus Nephritis Risk High Among Non-White Patients

Publish Date May 25, 2022

Researchers investigated the patient factors that affect risk for mortality and lupus nephritis among patients with SLE.

Bowman’s Capsule Rupture Linked to Poor Prognosis in Lupus Nephritis

Publish Date May 4, 2022

The integrity of Bowman’s capsule may play a role in the progression of lupus nephritis, according to investigators.

Belimumab May Reduce Organ Damage in SLE, Lupus Nephritis

Publish Date May 2, 2022

Belimumab is a monoclonal antibody that inhibits B-lymphocyte stimulator.

Infection Risk Varies by Lupus Nephritis Induction Therapy

Publish Date April 28, 2022

Adverse effects of induction therapies for lupus nephritis may limit their use.

Clinical Biomarkers of Lupus Nephritis Activity Unreliable

Publish Date April 20, 2022

Proteinuria and estimated glomerular filtration rate cannot accurately distinguish between ongoing inflammatory injury and chronic kidney damage in lupus nephritis, investigators pointed out.

Tacrolimus May Be an Alternative for First-Line Lupus Nephritis Therapy

Publish Date March 31, 2022

In a study, the calcineurin inhibitor tacrolimus proved to be noninferior to intravenous cyclophosphamide.

International Consensus Developed for Corticosteroid Dosing in Childhood-Onset SLE With Proliferative Lupus Nephritis

Publish Date March 29, 2022

Researchers developed a consensus-based standardized corticosteroid dosing regimen for patients with childhood-onset systemic lupus erythematosus with lupus nephritis.