Hyperuricemia

Methotrexate Added to Pegloticase for Gout Safe for Kidneys

Publish Date November 7, 2022

Investigators report findings from the MIRROR RCT trial, which compared pegloticase plus methotrexate vs placebo for uncontrolled gout.

Novel Febuxostat-Telmisartan Cocrystal May Treat Comorbid Hyperuricemia/Gout and Hypertension

Publish Date October 21, 2022

The novel cocrystal of febuxostat and telmisartan was evaluated for the treatment of comorbid hyperuricemia/gout and hypertension.

Trends in Serum Urate Monitoring Assessed Among Patients With Gout Receiving ULT

Publish Date October 6, 2022

Researchers used data from the ACR RISE registry to evaluate a treat-to-target approach among patients with gout receiving urate-lowering therapy.

Urate-Lowering Therapy May Be Renoprotective in Asymptomatic Hyperuricemia

Publish Date September 14, 2022

Clinicians currently decide whether or not to prescribe urate-lowering therapies in patients with asymptomatic hyperuricemia.

Fenofibrate-Associated Nephrotoxicity Common in Patients With Gout

Publish Date September 8, 2022

Researchers assessed the incidence and potential risk factors for the development offenofibrate-associated nephrotoxicity in patients with gout.

Racial Disparity in Gout Prevalence Revealed

Publish Date August 19, 2022

A study of US adults demonstrated that gout is significantly more common among Black vs White individuals, with the racial disparity possibly explained by diet, social determinants of health, and chronic kidney disease.

Cardiovascular Events More Likely After a Gout Flare

Publish Date August 8, 2022

Patients with gout flare have increased odds of cardiovascular events, independent of traditional cardiovascular risk factors.

High Serum Urate Levels Tied to Poor Outcomes, QOL, Function in Gout

Publish Date July 28, 2022

Researchers examined the associated changes in serum urate levels with health-related quality of life in patients with gout.

Allopurinol Dose Tied to Severe Cutaneous Reactions in CKD

Publish Date July 18, 2022

In a Canadian study, more than half of older adults with CKD initiated allopurinol at a higher-than-recommended dose.

Decreased Incidence and Risk for Dementia in Older Adult Patients With Gout

Publish Date July 13, 2022

Researchers investigated the association between gout and dementia in older adult patients.