Hyperuricemia

Hyperinsulinemic Diet May Increase Risk for Gout Among Women Older Than 30 Years

Publish Date November 29, 2021

In a prospective study, researchers analyzed the association between insulin-related dietary indices and risk for incident gout among US women older than 30 years.

Higher Uric Acid in Inpatient COVID-19 Cases Ups AKI Risk

Publish Date November 17, 2021

Patients with COVID-19 who had the highest quartile of serum uric acid at hospital admission had increased odds of acute kidney injury.

Gout Common in the US Dialysis Population

Publish Date November 16, 2021

New analysis suggests that gout prevalence is 21% among patients on peritoneal dialysis and 13% among those on hemodialysis.

Urate-Lowering Therapy Not Renoprotective When Kidney Function is Normal

Publish Date November 15, 2021

New findings complement previous research showing no renoprotective effect of urate-lowering therapy in patients with chronic kidney disease.

Pegloticase Effective for Uncontrolled Gout in Kidney Transplant Recipients

Publish Date November 12, 2021

In a study of kidney transplant recipients treated with pegloticase for uncontrolled gout, the proportion of patients experiencing gout flares declined over the treatment period.

Gout Risk Factors, Outcomes in Dialysis Population Characterized

Publish Date November 11, 2021

Some 15% of patients receiving dialysis in the United States have a gout diagnosis, according to a recent study.

Urate-Degrading Enzyme Fast Tracked for Hyperuricemia With Gout and CKD

Publish Date November 10, 2021

ALLN-346 is an investigational, first-in-class, nonabsorbed, orally-administered enzyme that breaks down urate in the gastrointestinal tract.

Response to Pegloticase Therapy Improved With Concomitant Methotrexate

Publish Date November 1, 2021

The double-blind, placebo-controlled MIRROR trial included 152 adults with uncontrolled gout.

Cardiovascular Risk Higher With Allopurinol vs Benzbromarone in Patients With Gout

Publish Date October 14, 2021

Researchers compared cardiovascular risk among patients with gout who received treatment with allopurinol vs benzbromarone.

Metagenomic Analysis Shows That the Gut Microbiome May Have a Role in Gout

Publish Date October 6, 2021

Researchers of a metagenomic analysis assessed the taxonomic and functional signatures of the gut microbiome in gout and its association with clinical parameters and response to therapeutic interventions.