Hyperuricemia

Gout May Be a Risk Factor for Aortic Stenosis Progression

Publish Date March 10, 2020

Aortic stenosis was found to worsen more frequently in patients with vs without gout.

Education and Better Physician Interaction May Improve Management of Gout

Publish Date March 18, 2020

Researchers sought to understand the unmet needs for patients and provide insight into achieving better treatment for gout.

Serum CA72-4 Elevated in Gout, Predicts Future Flares in Patients With Gouty Arthritis

Publish Date March 16, 2020

Researchers studied serum CA72-4 expression in patients with gout, and verified the hypothesis that CA72-4 was a predictor of future flares in gouty arthritis.

Liquid Formulation of Colchicine Now Available for Gout Management

Publish Date March 4, 2020

Avion Pharmaceuticals announced the launch of Gloperba (colchicine) oral solution for prophylaxis of gout flares in adults. Gloperba is a ready-to-use solution for oral administration containing 0.12mg/mL of colchicine. The approval was based on evidence from published literature supporting the efficacy of colchicine in patients with chronic gout. In 2 randomized clinical trials, treatment with…

Risk of Hypersensitivity Reactions Assessed With Commonly Used Gout Treatments

Publish Date March 4, 2020

Allopurinol and febuxostat were found to be associated with a higher risk of hypersensitivity reactions when compared to colchicine, according to the results of a recently published population-based study.

Gout Medication Safe, Effective in Dialysis Patients

Publish Date March 2, 2020

Febuxostat is safe and effective for treating gout in patients on dialysis, according to a new study. The study was a retrospective review of clinical and laboratory data from 62 dialysis patients (45 on hemodialysis and 17 on peritoneal dialysis) with gout treated with febuxostat. The mean serum uric acid level decreased significantly from 9.36…

OMERACT Structural Gout Lesions Sensitive to Change During Urate-Lowering Therapy

Publish Date February 24, 2020

The goal of this 6-month prospective observational study was to assess sensitivity to change of ultrasound structural gout lesions, as defined by the OMERACT ultrasound group, among patients with gout undergoing urate-lowering therapy.

Serum Urate-Associated Genetic Variants Strongly Contribute to Gout Risk Regardless of Diuretic Use

Publish Date February 14, 2020

Researchers determined the effect of serum urate-associated genetic variants on gout risk in individuals receiving diuretics vs those who were not.

Treat-to-Target Approach May Improve Renal Function in Patients With Gout and Chronic Kidney Disease

Publish Date February 26, 2020

Researchers assessed changes in the estimated glomerular filtration rate among patients with gout with moderate renal impairment, using a treat-to-target approach for gout.

Tart Cherry Concentrate Does Not Affect Serum Urate Levels in Patients With Gout

Publish Date January 16, 2020

Researchers determined the magnitude of the effect of tart cherry concentrate, including its dose and duration of use, on lowering serum urate levels in patients with gout.