Hyperuricemia

Allopurinol Found Not to Prevent Kidney Disease Progression in Key Populations

Publish Date June 25, 2020

In separate randomized controlled trials, allopurinol had no significant effect on kidney function decline.

Updated 2020 American College of Rheumatology Gout Management Guidelines

Publish Date June 24, 2020

The American College of Rheumatology developed guidelines for the management of gout, including use of urate-lowering therapy, flare treatment, and lifestyle and medication recommendations.

Azathioprine May Increase Pegloticase Responsiveness in Chronic Refractory Gout

Publish Date June 16, 2020

Researchers determined the effect of azathioprine on the frequency of chronic refractory gout among patients who had persistent urate lowering from pegloticase therapy.

Allopurinol Not Associated With Increased All-Cause Mortality in Gout

Publish Date June 2, 2020

Researchers evaluated the association between allopurinol use and mortality in patients with gout.

Hyperuricemia and Kidney Disease May Be Predictors of Subsequent Flares in Patients With Gout

Publish Date May 5, 2020

Researchers examined the changes in the presentation of incident gout in the last20 years and determined risk for subsequent gout flares after an initial gout attack.

Serum Urate Does Not Have a Causal Effect on Gout Comorbidity Risk, According to Mendelian Randomization Studies

Publish Date April 16, 2020

Researchers reviewed the causal relationships between gout, hyperuricemia, and associated comorbidities.

Hypertension Risk Increases as Uric Acid Levels Rise

Publish Date April 13, 2020

Elevated serum uric acid (SUA) levels are associated with development of hypertension and vascular and renal target organ damage, according to a new long-term study. Investigators studied 961 parents and 570 children who were initially healthy at the time of recruitment into the STANISLAS cohort, a single-center familial longitudinal cohort that began recruiting patients in…

Gout May Be a Risk Factor for Aortic Stenosis Progression

Publish Date March 10, 2020

Aortic stenosis was found to worsen more frequently in patients with vs without gout.

Education and Better Physician Interaction May Improve Management of Gout

Publish Date March 18, 2020

Researchers sought to understand the unmet needs for patients and provide insight into achieving better treatment for gout.

Serum CA72-4 Elevated in Gout, Predicts Future Flares in Patients With Gouty Arthritis

Publish Date March 16, 2020

Researchers studied serum CA72-4 expression in patients with gout, and verified the hypothesis that CA72-4 was a predictor of future flares in gouty arthritis.