Hyperuricemia News, Treatment Articles

DECT-Detected Cardiovascular Monosodium Urate Deposits More Common in Patients With Gout

October 15, 2019

Researchers assessed coronary calcium score and cardiovascular monosodium urate deposits detected by dual-energy computed tomography in patients with gout vs healthy controls.

Gout Risk During Tuberculosis Treatment Higher With Obesity, Chronic Kidney Disease, Hyperuricemia

October 4, 2019

Researchers investigated the clinical features and risk factors for gout during tuberculosis treatment in a South Korean population.

Better mCRPC Survival with Docetaxel Followed by Abiraterone

Heart Disease May Up Risk for Allopurinol-Linked Cutaneous AEs

September 30, 2019

Risk for hospital admission increased for allopurinol-associated severe cutaneous adverse reactions

Canagliflozin May Reduce Gout-Related Adverse Events, Uric Acid Levels in T2D

September 18, 2019

Researchers investigated the effects of canagliflozin on serum urate levels and gout in patients with type 2 diabetes.

Patients are often unaware of their increased CV risk related to RA. One study found 95% of patients with RA stratified as having a high risk of CVD underestimated their risk.17 Data show patients with RA are less likely to report angina symptoms, which increases their chances of an unrecognized MI or sudden cardiac death and decreases their likelihood of getting a needed coronary artery bypass graft.18 Some studies have shown interventions to educate RA patients about their risk of CVD have the potential to increase screening for CV risk by PCPs and treatment.19,20 Results from other studies have been less positive. One trial found although educational interventions improved patients’ understanding of their CV risk and prompted intentions to make lifestyle changes, patients did not carry through with their stated intentions.21 Nevertheless, patients should be made aware of all important aspects of their disease.

Gout Flare Variation Hinders Reporting in Clinical Trials

September 12, 2019

The study describes the variations of gout flares and assesses the different methods of gout flare reporting in clinical trials.

Febuxostat Safer Than Allopurinol for Asymptomatic Hyperuricemia

August 23, 2019

The researchers assessed the effects of febuxostat and allopurinol on mortality and adverse reactions in patients with hyperuricemia and gout.

Gout Increases Risk of Advanced Chronic Kidney Disease

August 28, 2019

In a large study of patients in the United Kingdom, patients with gout had a 29% increased risk of advanced CKD and 210% increased risk of end-stage renal disease compared with patients who did not have gout.

Hemodialysis Patients Face Higher Hip Fracture Risk

High Uric Acid Increases Death Risk in Peritoneal Dialysis

August 9, 2019

In patients on peritoneal dialysis, serum uric acid levels in the highest quintile are associated with a nearly 1.5-fold increased risk of all-cause mortality compared with levels in the third quintile, a study found.

a couple sitting on the couch holding hands

Gout Risk Factors Typically Similar for Men and Women

July 31, 2019

This systematic review identified several risk factors for the development of gout, with the degree of risk between the sexes predominantly being consistent.

Persistent Urate Lowering With Pegloticase Shows Clinical Benefits in Gout

July 18, 2019

Analysis indicated that patients with chronic refractory gout, not achieving a protocol-defined biochemical response, might still have significant clinical benefits with pegloticase treatment.

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