In patients on peritoneal dialysis, serum uric acid levels in the highest quintile are associated with a nearly 1.5-fold increased risk of all-cause mortality compared with levels in the third quintile, a study found.
This systematic review identified several risk factors for the development of gout, with the degree of risk between the sexes predominantly being consistent.
Analysis indicated that patients with chronic refractory gout, not achieving a protocol-defined biochemical response, might still have significant clinical benefits with pegloticase treatment.
Crystal deposition may still be present in patients with gout who fulfill the provisional gout remission criteria.
Although prior research indicates that gout increases risk for death because of cardiovascular complications, these data highlight elevated mortality from noncardiovascular causes.
Opioids are commonly prescribed for acute gout management following discharge from the emergency department.
Kidney transplant recipients have a higher prevalence of severe uncontrolled gout and higher rates of allopurinol discontinuation.
Gout was associated with increased risk for readmission for either a cardiovascular event or heart failure, and was associated with longer hospital stays in patients with acute coronary syndrome.
Dual-energy computed tomography showed good diagnostic accuracy in established gout but had low diagnostic sensitivity in patients with recent-onset gout.
Findings showed no difference in the risk of non-fatal cardiovascular outcomes and all-cause mortality between allopurinol and febuxostat treatment in patients with gout.