Chronic kidney disease is 3 times more likely to develop among individuals with vs without gout, according to a large retrospective cohort study.
Investigators evaluated the prevalence, distribution, and factors associated with bone erosion detectable by ultrasound in patients with gout.
Hospitalized men and women in the highest quartile of serum uric acid had a 3-fold higher risk of acute kidney injury than those in the lowest quartile.
In a meta-analysis, the risk for cardiovascular mortality increased a significant 12% for every 1 mg/dL increase in uric acid.
Investigators report a significant 27% increased risk of Parkinson’s disease among individuals aged 65 years and older but less than 75 years.
A history of gout was associated with worse outcomes in patients with obstructive coronary artery disease.
In an observational UK study, chronic kidney disease stage 3 or higher was 78% more likely to develop in patients with vs without gout during a median follow-up of 6 years.
Allopurinol use is not associated with renal function decline among those with newly diagnosed gout.
Study reveals an 11% prevalence of active gout among solid organ transplant recipients overall and a 13% prevalence among kidney transplant recipients.
Patients with chronic kidney disease who have hyperuricemia have a 3-fold higher risk of all-cause mortality.