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Hyperuricemia
The adjusted rate of venous thromboembolism was 2.3-fold higher during the first 30 days after gout flare compared with baseline.
Elevated serum uric acid levels showed significant relationships with all-cause and cardiovascular death, but not cancer death.
A majority of patients with hyperuricemia had NAFLD, investigators reported.
Major effects of febuxostat on renal outcome might be uric acid dependent, according to investigators.
Researchers studied the association between hospitalization and major cardiovascular events among patients with acute gout.
Optimizing management of gout may involve use of medications besides urate-lowering therapies.
The increased risk for gout associated with proton pump inhibitor use was more pronounced in women.
The choice and dosage of drugs may need to be modified when treating gout in patients with chronic kidney disease.
Hyperuricemia may contribute to heart failure risk via increased oxidative stress, endothelial dysfunction, inflammation, and insulin resistance, according to investigators.
Study confirms that hyperuricemia can be reduced by dietary approaches.
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