The authors reviewed the effects of urate-lowering therapy on cardiovascular disease in patients with gout.
As previous studies indicated that all-cause hospitalizations in patients with gout in the United States have overwhelmingly increased by 410% in the last 22 years, researchers sought to determine the potential reasons for the excess hospitalizations.
Dietary omega-3 polyunsaturated fatty acid-rich fish consumption, when adjusted for total purine intake, was associated with lower risk for recurrent gout flares.
Chronic kidney disease is 3 times more likely to develop among individuals with vs without gout, according to a large retrospective cohort study.
Investigators evaluated the prevalence, distribution, and factors associated with bone erosion detectable by ultrasound in patients with gout.
Hospitalized men and women in the highest quartile of serum uric acid had a 3-fold higher risk of acute kidney injury than those in the lowest quartile.
In a meta-analysis, the risk for cardiovascular mortality increased a significant 12% for every 1 mg/dL increase in uric acid.
Investigators report a significant 27% increased risk of Parkinson’s disease among individuals aged 65 years and older but less than 75 years.
A history of gout was associated with worse outcomes in patients with obstructive coronary artery disease.
In an observational UK study, chronic kidney disease stage 3 or higher was 78% more likely to develop in patients with vs without gout during a median follow-up of 6 years.