(HealthDay News) — The global rate of hypertension and prehypertension rose significantly between 1990 and 2015, according to a report published in the Journal of the American Medical Association.

Researchers reviewed 844 studies from 154 countries. The studies were published from 1980 to 2015 and included 8.69 million people.

Over those years, the annual mortality rate rose from 135.6 to 145.2 per 100,000 among those with a systolic pressure of at least 110 to 115 mm Hg. Among those with systolic pressure of 140 mm Hg or more, the annual mortality rate increased from 97.9 to 106.3 per 100,000, the researchers found. Most blood pressure-related deaths were caused by ischemic heart disease and stroke. 5 countries — the United States, China, India, Indonesia, and Russia — accounted for more than 50% of elevated or high blood pressure cases.

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According to study coauthor Gregory Roth, MD, an assistant professor of cardiology at the University of Washington in Seattle, the researchers chose to look at blood pressures at 110 to 115 mm Hg — well below the clinical definition of high blood pressure — because this is where the risk of high blood pressure begins. “The definition of hypertension is a systolic pressure greater than 140 mm Hg. However, there is very strong evidence that the risk of having an elevated blood pressure begins above 115 mm Hg,” Roth told HealthDay.

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  1. Forouzanfa MH, Liu P, Roth GA, et al. Global Burden of Hypertension and Systolic Blood Pressure of at Least 110 to 115 mm Hg, 1990-2015. JAMA. 10 January 2017. doi:10.1001/jama.2016.19043