(HealthDay News) — Aspirin use is underused for preeclampsia prophylaxis in women with prepregnancy diabetes, obesity, or chronic hypertension or a combination of these factors, according to a research letter published in the  Journal of the American Medical Association.

Joel G. Ray, MD, from St. Michael’s Hospital in Toronto, and colleagues used data from the Better Outcomes Registry and Network to identify women with a hospital livebirth or stillbirth at ≥23 weeks of gestation (371,237 births; April 1, 2018, through Dec. 31, 2020) to estimate aspirin use for preeclampsia prevention in pregnant women with prepregnancy diabetes, obesity, chronic hypertension, and combinations of these factors.

The researchers found that aspirin was used by 3.2% of women without any of the three risk factors versus 17.2% of women with diabetes, 6.9% of women with obesity, and 27.6% of women with hypertension. For women with diabetes and obesity, the rate of aspirin use was 22.2% versus 36.6% in women with diabetes and hypertension, 32.3% in women with obesity and hypertension, and 38.8% in women with all three factors.

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“For the 2021 US Preventive Services Task Force recommendations to be more influential, more data are needed to characterize barriers for aspirin adoption among suitable women at the patient and practitioner level, and additional knowledge translation initiatives developed,” the authors write.

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