Colorectal Cancer Risk Down With ACEi, ARB Use
Reduction in adjusted hazard ratio risk of colorectal cancer with each single year increase in drug use.
Hypertension
HYPERTENSION
Sacubitril/Valsartan Under Review for Heart Failure With Preserved Ejection Fraction
The FDA has accepted for review the supplemental New Drug Application (sNDA) for sacubitril/valsartan (Entresto; Novartis) in the treatment of heart failure with preserved ejection fraction.
Adherence to BP Meds Linked to Improved Survival in Frail Elderly Patients
Adherence to antihypertensive treatment was associated with a reduced risk of death among elderly patients, including frail individuals, according to a large study published in Hypertension.
Patiromer Enables Spironolactone Use in Advanced CKD With Heart Failure
According to a new analysis of the AMBER study, more heart failure patients treated with patiromer than placebo remained on spironolactone therapy at 12 weeks.
COVID-19 Mortality Higher for Those Not Taking Meds for Their Hypertension
Mortality similar with renin-angiotensin-aldosterone system inhibitor, non-RAAS inhibitor for hypertension.
COVID-19 Drug Studies Questioned
Journals issue ‘expressions of concern’ over two recent studies of medications and their effect on COVID-19 patients.
Intensive Blood Pressure Control Tied to Lower Atrial Fibrillation Risk
Lowering systolic BP to <120 mm Hg lowers risk by 26%.
Thigh Circumference Tied to Hypertension Risk
Larger thighs tied to lower risk for hypertension in overweight, obese Chinese population.
For Those With Heart Failure, ACE2 Concentrations Up in Men
Use of ACE inhibitors, ARBs not tied to higher plasma ACE2 concentrations in those with heart failure.
ACE Inhibitor/ARB Use Not Tied to COVID-19 Test Positivity
No significant association identified in overlap propensity score weighting analysis.
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