Hyperphosphatemia

Real-World Phosphate Binder Use Described

Publish Date April 12, 2022

Nearly two-thirds of patients receiving dialysis use phosphate binders intermittently, a study found.

CKD-MBD Marker Changes Vary Across Dialysis Modalities

Publish Date March 15, 2022

Use of home dialysis and modalities other than conventional in-center hemodialysis is expected to grow.

Hyperphosphatemia Slightly Reduces Calcimimetics’ Effects

Publish Date January 14, 2022

Study findings suggest serum phosphate is a negative modulator of calcium receptor activation.

Potassium Binder May Also Lower Phosphate Levels in CKD

Publish Date November 19, 2021

Patiromer may be another therapeutic option for patients with both hyperkalemia and hyperphosphatemia.

RCT Data Needed on Phosphate-Lowering Agents and NDD-CKD Outcomes

Publish Date October 21, 2021

Systematic reviews on this topic have largely been focused on patients receiving dialysis.

Phosphate Binder Dissatisfaction May Affect Patient Outcomes

Publish Date September 28, 2021

Dissatisfaction with taking phosphate binders may influence medication adherence and ultimately clinical outcomes, according to investigators.

FDA Wants Another Study Before Deciding on Tenapanor Approval

Publish Date August 16, 2021

Tenapanor inhibits the sodium/hydrogen exchanger 3 to control serum phosphorus in adults with CKD on dialysis.

Tenapanor Monotherapy May Reduce Phosphorus Levels in Patients on Dialysis

Publish Date August 4, 2021

Full results from the OPTIMIZE study, due to be completed in August 2021, are forthcoming.

Tenapanor Reduces Phosphate Binder Pill Burden in Hemodialysis

Publish Date July 20, 2021

Unlike phosphate binders, tenapanor decreases paracellular phosphate absorption in the intestine.

In-Center Nocturnal Hemodialysis May Improve HRQOL

Publish Date June 30, 2021

In a small Canadian study, investigators found that patients switched from conventional to in-center nocturnal hemodialysis experience improvements in various measures of health-related quality of life, especially mental health.