Hyperphosphatemia

Nicotinamide May Improve Phosphate Control in Hemodialysis Patients

Publish Date March 10, 2021

Nicotinamide modulates expression of the sodium-dependent phosphate cotransporter 2b and thereby may inhibit intestinal phosphate absorption, according to investigators.

Investigators ID Factors Affecting Predialysis Hemoglobin Control

Publish Date March 5, 2021

Study findings reinforce the value of treating anemia during the transition to dialysis and illustrate the problem of ESA hyporesponsiveness.

Strict Phosphate Control May Slow Coronary Artery Calcification in HD

Publish Date February 25, 2021

Vascular calcification is the most likely mechanism underlying the association between hyperphosphatemia and mortality, according to investigators.

Phosphate Binder Found to Raise Blood Pressure in Chronic Kidney Disease

Publish Date February 3, 2021

Investigators found a clinically significant difference in systolic blood pressure among patients with stage 3b to 4 chronic kidney disease taking and not taking lanthanum carbonate.

Study: Controlling Bone Mineral Parameters in Advanced CKD May Up Survival

Publish Date January 25, 2021

Study data illustrate the potential benefits of controlling serum phosphate, intact parathyroid hormone, and calcium levels in patients with nondialysis-dependent chronic kidney disease.

CKD-MBD Testing, Monitoring Suboptimal in Advanced CKD

Publish Date January 25, 2021

In a large US study, only half of patients with stage 3, 4, and 5 had undergone PTH retesting at 12, 8, and 4.5 months, respectively, after treatment with vitamin D sterols, in line with KDIGO guidelines.

Therapeutic Advances in Kidney Failure Care Linked to Improved Survival

Publish Date January 20, 2021

Study results show that mortality among hemodialysis patients declined from 2006 to 2015 compared with the general Swedish population.

Minimal Interference Found Between Phosphate Binders, Daprodustat

Publish Date October 26, 2020

In a study, hemoglobin values did not differ meaningfully among daprodustat users, whether or not they also took one or more phosphate binders.

Risk of Nonspinal Fracture Increased in Moderate to Severe CKD

Publish Date October 13, 2020

Fracture prevention efforts should be considered in patients with CKD of any age, according to investigators.

Tenapanor Under Review for Hyperphosphatemia in CKD

Publish Date September 18, 2020

Tenapanor is a first-in-class oral medication that works by blocking the NHE3 transporter in the gastrointestinal tract.