Hyperphosphatemia

Study: Controlling Bone Mineral Parameters in Advanced CKD May Up Survival

Publish Date January 25, 2021

Study data illustrate the potential benefits of controlling serum phosphate, intact parathyroid hormone, and calcium levels in patients with nondialysis-dependent chronic kidney disease.

CKD-MBD Testing, Monitoring Suboptimal in Advanced CKD

Publish Date January 25, 2021

In a large US study, only half of patients with stage 3, 4, and 5 had undergone PTH retesting at 12, 8, and 4.5 months, respectively, after treatment with vitamin D sterols, in line with KDIGO guidelines.

Therapeutic Advances in Kidney Failure Care Linked to Improved Survival

Publish Date January 20, 2021

Study results show that mortality among hemodialysis patients declined from 2006 to 2015 compared with the general Swedish population.

Minimal Interference Found Between Phosphate Binders, Daprodustat

Publish Date October 26, 2020

In a study, hemoglobin values did not differ meaningfully among daprodustat users, whether or not they also took one or more phosphate binders.

Risk of Nonspinal Fracture Increased in Moderate to Severe CKD

Publish Date October 13, 2020

Fracture prevention efforts should be considered in patients with CKD of any age, according to investigators.

Tenapanor Under Review for Hyperphosphatemia in CKD

Publish Date September 18, 2020

Tenapanor is a first-in-class oral medication that works by blocking the NHE3 transporter in the gastrointestinal tract.

High Serum Phosphate Concentration May Be Associated With Greater MALE Risk in Hemodialysis

Publish Date June 26, 2020

Elevated serum phosphate concentration may be associated with an increased risk for major adverse limb events in patients undergoing hemodialysis.

Iron-Based Phosphate Binder Is Effective, Does Not Cause Iron Overload

Publish Date March 12, 2020

A study of stable dialysis patients receiving sucroferric oxyhydroxide found no significant changes in hemoglobin, ferritin level, and transferrin saturation.

Tighter Phosphate Control in HD May Slow Coronary Artery Calcification

Publish Date December 16, 2019

Achieving serum phosphate levels of 3.5 to 4.5 mg/dL vs 5.0 to 6.0 mg/dL in patients on hemodialysis was associated with less coronary artery calcification, study findings suggest.

Elevated Phosphate Worsens Inpatient Outcomes Regardless of Renal Function

Publish Date December 13, 2019

In a study of hospitalized patients, increased serum phosphate levels significant increased the risk of acute kidney injury, end-stage renal disease, and death.