Home short daily hemodialysis (SDHD) is associated with a decreased prevalence and severity of restless legs syndrome (RLS), according to a new report.

A team led by Bertrand L. Jaber, MD, of St. Elizabeth’s Medical Center in Boston, studied 127 SDHD patients participating in the ongoing prospective FREEDOM (Following Rehabilitation, Economics and Everyday-Dialysis Outcomes Measurements) study and who completed 12 months of follow-up.

Among the 40% of patients with RLS, the mean International Restless Legs Syndrome (IRLS) score improved significantly at month 12 compared with baseline, after adjusting for the use of RLS medications (18 vs. 11), investigators reported in the Clinical Journal of the American Society of Nephrology (published online ahead of print).

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Among subjects with moderate-to-severe RLS (IRLS score of 15 or higher), the score decreased from 23 at baseline to 13 at 12 months. In addition, the percentage of patients reporting RLS decreased from 35% to 26% and the percentage of those reporting moderate to severe RLS decreased from 59% to 43%.