Dialysis patients who take heart medications that are easily removed from the circulation through dialysis may be at increased risk of dying prematurely compared with patients whose heart medications are more difficult to remove. The findings come from a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).
Beta blockers—drugs used to control heart rhythm, treat angina, and reduce high blood pressure—lower the risk of premature death among people with heart disease who are not receiving dialysis. Beta blockers differ in their dialyzability, or the extent to which they are removed through hemodialysis, and experts suspect that if the filtering effects of dialysis remove these important drugs from the circulation, patients can’t experience their full benefit.
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