WASHINGTON, D.C.—Patients who develop heart failure (HF) after starting hemodialysis (HD) are at significantly elevated risk of death compared with those who do not, researchers reported at the American College of Cardiology annual meeting.
Abel E. Moreyra, MD, and colleagues at the Robert Wood Johnson Medical School in New Brunswick, N.J., studied 4,727 patients hospitalized for HF after HD initiation and 7,258 on HD who did not experience HF. The investigators matched patients for duration of dialysis up to the time of HF admission. Patients had up to 18 years of follow-up.
Compared with HD patients who did not develop HF, those who developed HF within 1 year of HD initiation had a 22% increased risk of death, after adjusting for demographics, health insurance, and etiology of renal failure. Patients who experienced HF 1-2 years, 2-3 years, 3-4 years, 4-5 years, and more than 5 years after starting HD had a 42%, 34%, 34%, 35%, and 26% increased risk of death, respectively.