(HealthDay News) — Timing of moderate-to-vigorous physical activity (MVPA) may be connected to cardiovascular fitness among men with type 2 diabetes, according to a study published online in Diabetes Care.

Jingyi Qian, PhD, from Brigham and Women’s Hospital in Boston, and colleagues examined the associations of timing of bout-related MVPA with cardiorespiratory fitness and cardiovascular risk in 2153 adults with type 2 diabetes. Bout-related MVPA was defined as 3 or more metabolic equivalent tasks per minute for ≥10 minutes and was determined through a hip-worn accelerometer.

The researchers found that cardiorespiratory fitness was highly associated with timing of bout-related MVPA, independent of weekly bout-related MVPA volume and intensity. There was a significant association by sex. The midday group had the lowest fitness in men, while the mixed group in women was the least fit. There was also a significant association between the Framingham risk score (FRS) and timing of bout-related MVPA, which also differed by sex. The highest 4-year FRS was seen among the male morning group, but there was no association seen in women.

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“Timing of bout-related MVPA is associated with cardiorespiratory fitness and cardiovascular risk in men with type 2 diabetes, independent of bout-related MVPA volume and intensity,” the authors write.

One author disclosed financial ties to the pharmaceutical and health care industries, and one serves on the advisory boards of weight-loss program companies.


Qian J, Walkup MP, Chen S-H, et al; the Look AHEAD Research Group. Association of objectively measured timing of physical activity bouts with cardiovascular health in type 2 diabetes. Diabetes Care 2021 Feb; dc202178. doi:10.2337/dc20-2178