(HealthDay News) — Individuals with the healthiest lifestyle have a 75% reduced risk for type 2 diabetes, and those with diabetes have a lower risk for mortality, according to a review published online in Diabetologia.

Yanbo Zhang, from Huazhong University of Science and Technology in Wuhan, China, and colleagues conducted a systematic review to examine the correlation between combined lifestyle factors (including smoking, alcohol drinking, physical activity, diet, and being overweight or obese) and the risk for incident type 2 diabetes and risk for health outcomes among individuals with diabetes.

The researchers found that participants with the healthiest lifestyle had a significantly reduced risk for incident diabetes compared with those considered to have the least healthy lifestyle (hazard ratio, 0.25; 95% confidence interval [CI], 0.18 to 0.35; 14 studies with about 1 million participants). Among individuals from different socioeconomic backgrounds and baseline characteristics, the associations were largely consistent and significant. When comparing the healthiest lifestyle with the least healthy lifestyle, the hazard ratios were 0.44 (95% CI, 0.33 to 0.60) for all-cause death, 0.51 (95% CI, 0.33 to 0.60) for cardiovascular death, 0.69 (95% CI, 0.47 to 1.00) for cancer death, and 0.48 (95% CI, 0.37 to 0.63) for incident cardiovascular death among individuals with type 2 diabetes (10 studies; 34,385 participants).

“Given the proportion of individuals with the healthiest lifestyle was low in most populations, promotion of an overall healthy lifestyle, instead of tackling one particular lifestyle factor, should be a public health priority for all countries,” the authors write.


Zhang Y, Pan XF, Chen J, et al. Combined lifestyle factors and risk of incident type 2 diabetes and prognosis among individuals with type 2 diabetes: a systematic review and meta-analysis of prospective cohort studies. Diabetologia.