Shock wave lithotripsy is not associated with an increased risk of developing diabetes mellitus, researchers reported.

The investigators noted that there is concern about diabetes mellitus resulting from SWL because cases studies have shown that the pancreas is vulnerable to injury from the treatment.

Amy E. Krambeck, MD, of the Mayo Clinic College of Medicine in Rochester, Minn., and colleagues studied 5,287 cases of stone formation in patients without pre-existing diabetes mellitus and at least three months of follow-up. After an average follow-up of 8.7 years, 423 patients (8%) underwent SWL treatment, according to findings published in Urology (online ahead of print). New-onset diabetes mellitus developed in 743 (12%). For 77 patients, the diabetes diagnosis followed SWL. After controlling for age, gender, and obesity, the investigators found no significant association between SWL and diabetes mellitus.

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