(HealthDay News) — Rotating shift work which includes night shifts is associated with increased odds of type 2 diabetes, according to a study published online in Diabetes Care.

Céline Vetter, PhD, from the University of Colorado in Boulder, and colleagues examined associations of current and lifetime night shift work exposure (272,214 and 70,480 participants, respectively) with type 2 diabetes risk (6,770 and 1191 prevalent cases, respectively).

The researchers found that all current night shift workers were at higher multivariable-adjusted odds for type 2 diabetes compared with day workers (odds ratios [OR], 1.15 [95% confidence interval (CI), 1.05 to 1.26], 1.18 [95 % CI, 1.05 to 1.32], and 1.44 [95% CI, 1.19 to 1.73] for none or rare night shifts, some nights, and usual nights), except for current permanent night shift workers (odds ratio, 1.09 [95% CI, 0.93 to 1.27]). Working more night shifts per month correlated with increased odds of type 2 diabetes considering a person’s lifetime work schedule and compared with never shift workers (<3/month: OR, 1.24 [95% CI, 0.90 to 1.68]; 3 to 8/month: OR, 1.11 [95% CI, 0.90 to 1.37]; and >8/month: OR, 1.36 [95% CI, 1.14 to 1.62]).

“Night shift work, especially rotating shift work including night shifts, is associated with higher type 2 diabetes odds and that the number of night shifts worked per month appears most relevant for type 2 diabetes odds,” the authors write.

Two authors disclosed financial ties to the pharmaceutical and other industries.

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Vetter C, Dashti HS, Lane JM, et al. Night Shift Work, Genetic Risk, and Type 2 Diabetes in the UK Biobank. Diab Care 2018 Feb;dc171933. doi:10.2337/dc17-1933