(HealthDay News) — Perioperative major adverse cardiovascular and cerebrovascular events (MACCEs) are more common among patients with diabetes mellitus (DM), according to a study published online in Diabetes Care.

Jonathan D. Newman, MD, MPH, from the New York University School of Medicine in New York City, and colleagues used data from the US National Inpatient Sample to identify 10,581,621 hospitalizations for major noncardiac surgery in patients ≥45 years of age from January 2004 to December 2013. Diabetes status was determined, and perioperative MACCEs by diabetes status were assessed over time.

The researchers found that approximately 23% of patients had DM and that the rate of DM increased over time. MACCEs occurred in patients with DM in 3.3% of surgeries versus in 2.8% of surgeries for patients without DM. The odds of perioperative MACCEs increased over the study period, after multivariable adjustment, by 6% for DM patients compared with an 8% decrease for patients without DM.

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“Our findings suggest that a substantial unmet need exists for strategies to reduce the risk of perioperative cardiovascular events among patients with DM,” the authors write.

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Newman JD, Wilcox T, Smilowitz NR, and Berger JS. Influence of Diabetes on Trends in Perioperative Cardiovascular Events. Diab Care 2018 Apr;dc172046. DOI: 10.2337/dc17-2046