(HealthDay News) — For patients with type 2 diabetes, hip fracture is associated with an increased risk for death, according to a study published online May 21 in the Journal of Diabetes Investigation.

Yuji Komorita, MD, PhD, from Kyushu University in Fukuoka, Japan, and colleagues examined the correlations of hip fracture, upper-limb fracture, cardiovascular disease (CVD), and end-stage renal disease (ESRD) with all-cause death in patients with type 2 diabetes. A total of 4923 Japanese patients with type 2 diabetes were followed for a median of 5.3 years.

The researchers found that during follow-up, 309 participants died. Participants with hip fracture versus those without had increased multivariate-adjusted odds ratios (ORs) for all-cause mortality (OR, 2.67). The ORs for upper-limb fractures were not significant. Patients with CVD and ESRD versus those without had significantly higher ORs for all-cause mortality (ORs, 1.78 and 2.36, respectively). Further adjustment for CVD and ESRD did not affect the OR for all-cause mortality associated with hip fracture (OR, 2.74). Among participants with hip fracture, the cause of death was infection, malignant neoplasm, and CVD (40, 25, and 15%, respectively).

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“It should be emphasized that hip fracture is a critical event in the aging population of patients with type 2 diabetes during the present era of a better prognosis of CVD,” the authors write.


Komorita Y, Iwase M, Idewaki Y, et al. Impact of hip fracture on all‐cause mortality in Japanese patients with type 2 diabetes mellitus: the Fukuoka Diabetes Registry. J Diab Inves.