Gout increases the risk for type 2 diabetes, and this effect is more pronounced in women than men, according to a new study.

Using a population-based representative insurance claims database, Hung-Pin Tu, PhD, Kaohsiung Medical University, Kaohsiung, Taiwan, and colleagues studied 29,765 patients with gout and 59,530 without gout (controls). Type 2 diabetes developed in 3940 gout patients (13.24%) and 6334 controls (10.64%). Compared with controls, gout patients overall had a significant 70% increased risk of type 2 diabetes in multivariable analysis, the investigators reported online ahead of print in the American Journal of Medicine. Gout increased the risk of type 2 diabetes nearly 2-fold in women compared with 1.62 times in men, a significant difference.

In addition, compared with men who did not have gout, women without gout had a significantly higher risk of type 2 diabetes.

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“Gout is strong and independent risk factor for type 2 diabetes, and female patients with gout are at a higher risk of type 2 diabetes than are male patients with gout,” the investigators concluded.

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