Contrast Nephropathy

Hepcidin May Enable Early Ruling Out of Contrast-Induced AKI

Publish Date March 6, 2019

Serum hepcidin rises significantly as early as 4 and 8 hours after percutaneous coronary intervention.

Gadolinium-Based Contrast May Up Acute Kidney Injury Risk in CKD

Publish Date November 16, 2018

The risk of post-contrast acute kidney injury increased with decreasing renal function.

Ultra-low Contrast Volume May Protect Kidneys in Advanced CKD

Publish Date January 31, 2018

No patient had a 25% or greater rise in serum creatinine 48 hours after receiving a median 13 mL of contrast for diagnostic coronary angiography, with an additional 13 mL for percutaneous coronary intervention.

Nicorandil May Prevent Contrast-induced Nephropathy

Publish Date January 17, 2018

Nicorandil significantly reduced contrast-induced nephropathy by 62%, compared with controls.

IV Sodium Bicarbonate Does Not Reduce AKI Risk After Angiography

Publish Date November 13, 2017

Contrast-associated acute kidney injury occurred in 9.5% and 9.1% of patients receiving IV sodium bicarbonate and acetylcysteine, respectively, rates which did not differ significantly from the 8.3% rate among those receiving IV sodium chloride.

AKI More Likely After Intracoronary Versus IV Contrast Delivery

Publish Date November 4, 2017

In a phase 3 trial, acute kidney injury developed in 13.2% of patients undergoing invasive coronary angiography compared with 5.6% of those undergoing computed tomography angiography.

AKI After Computed Tomography Not Tied to Contrast

Publish Date August 29, 2017

AKI occurred with similar frequency among patients who did and did not receive contrast medium.

Risk Factors for Contrast-Induced AKI in Transplant Patients ID’d

Publish Date May 1, 2017

Risk factors include impaired renal function and inadequate hydration prior to contrast exposure.

Study Questions Prophylactic Hydration as Standard Care for CIN

Publish Date March 23, 2017

High-risk patients who did not receive guidelines-recommended prophylactic hydration prior to procedures requiring iodinated contrast media had the same rate of contrast-induced nephropathy (CIN) as patients who received usual care, according to results from the phase 3 AMACING trial published online ahead of print in The Lancet.1 CIN refers to the decline in renal function…

Furosemide With Matched Hydration Prevents Contrast Nephropathy

Publish Date February 23, 2017

Compared with control treatment, RenalGuard therapy correlated with significantly reduced CI-AKI, as well as a reduced need for renal replacement therapy.