Self-reported appetite in children with chronic kidney disease (CKD) worsens with lower glomerular filtration rate. 

In a study of 879 participants in the Chronic Kidney Disease in Children study, Frank W. Ayestaran, MD, of Emory University in Atlanta, and colleagues found that children with an iohexol or estimated glomerular filtration rate (ieGFR) below 30 mL/min/1.73 m2 was associated with nearly 4.5-fold greater odds of having a worse appetite than those with an ieGFR above 90 mL/min/1.73 m2, according to an online report in Pediatric Nephrology. Patients who did not have a very good appetite had more hospitalizations over the following year than those with a very good appetite.