New research by a Yale University scientist suggests that muscle mass is not as accurate a predictor of chronic kidney disease outcomes as previously thought. In a study published online Nov. 7 by the Clinical Journal of the American Society of Nephrology, researchers looked at data from 3,604 patients with chronic kidney disease. They checked for an association between CKD outcomes (death and dialysis) and a pair of factors related to muscle mass.
Muscle mass has been shown to be predictive of these outcomes in other disease states. For the first factor, creatinine excretion in urine, doctors did find an association. Lower levels of urinary creatinine excretion were “strongly” associated with increased mortality and progression to end-stage renal disease.
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