Early-stage chronic kidney disease(CKD) may be an independent riskfactor for increased carotid intima-mediathickness (IMT), a biomarker ofatherosclerosis, according to findingspublished online in the Journal ofStroke and Cerebrovascular Diseases.

In a study of 3,629 individualswithout clinical cardiovascular diseaseat baseline, Yu Wu, PhD, of BeijingTiantan Hospital, Capital Medical University,Beijing, China, and colleaguesfound that subjects with an estimatedglomerular filtration rate (eGFR) of60–89 and 30–59 mL/min/1.73m2, respectively, had 30% and 79%greater odds of increased IMT afteradjusting for age and traditional cardiovascularrisk factors.