In a study, patients with chronic kidney disease (CKD) who had the highest healthy lifestyle scores (did not smoke, followed a healthful diet, and maintained a body mass index above 22 kg/m2) were 53% less likely to die from any cause than those with the lowest healthy lifestyle scores, according to data published online ahead of print in the Clinical Journal of the American Society of Nephrology.

After a median follow-up of 13 years and the deaths of 1,319 of the 2,288 original participants with CKD (estimated glomerular filtration rate lower than 60 mL/min/1.73m2 or microalbuminuria), Ana C. Ricardo, MD, of the University of Illinois Hospital and Health Sciences System, and colleagues found that mortality increased by 30% among patients with a BMI of 18.5 to less than 22 kg/m2 compared with a BMI of 22 to less than 25 kg/m2.

The mortality risk was 46% lower for never-smokers than for current smokers, and 20% lower for subjects who were regularly physically active compared with those who engaged in no physical activity. Diet was not significantly associated with mortality.

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