Gout is the most prevalent inflammatory arthritis, affecting 2.4% of adults in the UK. Gout is associated with considerable co-morbidity including hypertension, diabetes mellitus, obesity, metabolic syndrome, and vascular disease. 

Associations between gout and renal disease and nephrolithiasis have long been recognised, yet early studies undertaken in specialist secondary care populations are likely to be unrepresentative of most patients with gout who are managed exclusively in primary care settings. To the best of our knowledge, no previous systematic reviews examining this association have been performed.

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