Coffee consumption does not worsen the course of autosomal dominant polycystic kidney disease (ADPKD), researchers reported online ahead of print in the Journal of Nephrology.

Prior in vitro studies of human PKD cells identified caffeine as a risk factor for promoting cyst enlargement in ADPKD patients.

In a prospective longitudinal study of 151 ADPKD patients with a median follow-up time of 4.38 years, Laura Girardat-Rotar, of the University of Zurich in Switzerland, and colleagues found that coffee drinkers did not have a statistically significant difference in kidney size or estimated glomerular filtration rate compared with those who did not drink coffee.

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