Increasing body mass index (BMI) and waist circumference are associated with elevated risks of secondary hyperparathyroidism and other complications in patients with chronic kidney disease (CKD), researchers reported in the American Journal of Nephrology (2012;36:219-227).

In a study of 2,853 adult participants with CKD in the National Health and Nutrition Examination Surveys (1999-2006), Sankar D. Navaneethan, MD, MPH, of Cleveland Clinic, and colleagues found that a two-point increment in BMI and a 5 cm increment in waist circumference were associated with increased odds of secondary hyperparathyroidism, hypoalbuminemia, and hypertension.

Compared with subjects who had a BMI below 30 kg/m2, those with a higher BMI had increased odds of hypoalbuminemia and hypertension. Individuals with a high waist circumference (greater than 102 cm for men and greater than 88 cm for women) had higher odds of hypoalbuminemia and hypertension and lower odds of having anemia than those with a low waist circumference.

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