The current guideline-recommended creatinine-based eGFR equation incorporates a race coefficient that may overestimate eGFR in Black adults and contribute to discordant care.
Despite similar risk for albuminuria with diabetes, albumin-to-creatinine ratio screening in patients with hypertension remains very low
Investigators examined the urate-lowering effects of febuxostat, allopurinol, and benzbromarone and their association with renal protection in CKD.
Investigators report increased risks for adverse pathology and 90-day readmission.
In FIDELITY, investigators pooled data from more than 13,000 patients from the FIDELIO-DKD and FIGARO-DKD trials.
Using changes in UACR and eGFR as an alternative outcome for kidney failure in trials of CKD progression warrants further evaluation, according to investigators.
Hyperkalemia signals diminished kidney function and lasting risks to kidney health, according to investigators.
The approval was based on data from the pivotal phase 3 KALM-1 and KALM-2 trials, as well as data from an additional 32 clinical studies.
High variability in body mass index is associated with an increased risk for death, requiring kidney replacement therapy, myocardial infarction, and stroke, investigators concluded.
Variability in heart failure risk among women and men with CKD is particularly relevant given its high prevalence, according to investigators.