Kidney disease is a global public health problem, affecting over 750 million persons worldwide.1,2 The burden of kidney disease varies substantially across the world, as does its detection and treatment. In many settings, rates of kidney disease and the provision of its care are defined by socio-economic, cultural and political factors leading to significant disparities.3 World Kidney…
Almost half of incident hyperkalemia events are followed by changes in RAAS inhibitor therapy.
In a study, CKD patients with OSA treated with nasal continuous positive airway pressure (CPAP) had significantly higher eGFR after 12 months of treatment than those not receiving CPAP.
Proliferative vs non-proliferative diabetic retinopathy in CKD patients is associated with a higher risk of CKD progression.
Laboratory testing for parathyroid hormone, phosphorus, 25-hydroxyvitamin D, and other biochemical markers of mineral bone disease falls short of 2012 KDIGO guidelines.
Longitudinal renal function trajectories may enable more individualized prediction of adverse outcomes, researchers conclude. Faster kidney disease progression is associated with an increased risk of adverse outcomes in patients with both atrial fibrillation (AF) and chronic kidney disease (CKD), new data suggest. In a study of 18,240 patients with AF and stage 3–4 CKD, each…
New model predicts that maintenance of normal potassium levels in CKD patients to optimize use of renin-angiotensin-aldosterone inhibitors can delay progression to ESRD and prolong survival.
Study results point to a future when whole exome sequencing will be the method of choice for identifying genetic causes of CKD.
Longer follow-up intervals than recommended in current guidelines may be appropriate.
Whole exome sequencing, a technique for sequencing the protein-coding genes in the genome, can identify multiple potential genetic causes of inherited kidney disease, according to investigators. Their study of exome sequencing and diagnostic analysis involving 2 cohorts totaling 3315 patients with chronic kidney disease (CKD) detected diagnostic variants in 307 patients (9.3%). Of these, 206…