HealthDay News — For patients after acute myocardial infarction, rehospitalization for unstable angina (UA) and unplanned revascularization during the first year are associated with worse health status, according to a study published online in Circulation: Cardiovascular Quality and Outcomes.
Supriya Shore, MD, from the Emory University School of Medicine in Atlanta, and colleagues assessed health status for 3283 patients with acute myocardial infarction enrolled in a prospective, 24-center US study who had rehospitalizations. In propensity-matched cohorts, one-year health status was compared for those who did and did not experience rehospitalization for UA or revascularization.
The researchers found that at one year, the rehospitalization rates for UA and unplanned revascularization were 4.3 and 4.7%, respectively. Compared with patients without rehospitalizations, those with rehospitalizations for UA and unplanned revascularization had worse one-year Seattle Angina Questionnaire summary scores (mean difference, −10.1 and −5.7, respectively). The EuroQol-5D Visual Analog Scale scores were also worse with rehospitalizations. Among patients rehospitalized for UA or unplanned revascularization, worse one-year angina and quality-of-life outcomes were seen with individual Seattle Angina Questionnaire domains.
“These findings highlight the impact of such events from a patient’s perspective, beyond their economic impact, and support the use of UA and unplanned revascularization as elements of composite end points,” the authors write.
Several authors disclosed financial ties to medical device and pharmaceutical companies, including Eli Lilly, which provided funding for the study; one author owns the copyright to the Seattle Angina Questionnaire.
- Shore S, Smolderen KG, Kennedy KF, et al. Health Status Outcomes in Patients With Acute Myocardial Infarction After Rehospitalization. Circ Cardiovasc Qual Outcomes. 2016 Oct 25. http://dx.doi.org/10.1161/CIRCOUTCOMES.116.002883