Hospitalization rates for acute kidney injury (AKI) in men and women increased from 2000 to 2014 in the United States, according to findings published in Morbidity and Mortality Weekly Report (MMWR.

Using data from the National Inpatient Sample and the National Health Interview Survey, investigators at the Centers for Disease Control and Prevention (CDC) determined that AKI hospitalizations increased from 23.1 to 55.3 per 1000 persons, or 139%, in patients with diabetes. Among those without diabetes, AKI hospitalizations increased from 3.5 to 11.7 per 1000 persons, or 230%. Patients with diabetes were 4 times more likely to be hospitalized with AKI. Trends in dialysis-treated AKI were similar. Data from other countries likewise suggest an overall rise in AKI hospitalizations.

Greater survival among patients with diabetes, along with higher rates of septicemia, shock, congestive heart failure, and liver disease, might be contributing to the increase, according to study authors Meda E. Pavkov, MD, PhD, and colleagues from CDC’s Division for Diabetes Translation.

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“Improving both patient and provider awareness that diabetes, hypertension, and advancing age are frequently associated with acute kidney injury might reduce its occurrence and improve management of the underlying diseases in an aging population,” Dr Pavkov and her co-authors wrote.

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Pavkov ME, Harding JL, and Burrows NR. Trends in hospitalizations for acute kidney injury — United States, 2000–2014. MMWR. March 16, 2018 67(10);289–293.