RAASi, Diuretic Use Ups Acute Kidney Injury Risk
Clinicians should weigh the benefits and risks of renin-angiotensin-aldosterone-system inhibitors and diuretics, according to investigators.
Acute Kidney Injury
ACUTE KIDNEY INJURY
Greater Use of Deceased Donor AKI Kidneys Urged
A large study found similar graft survival rates between deceased donor kidneys with and without acute kidney injury.
Risk of Acute Kidney Injury With SGLT2 Inhibitors Investigated
Sodium-glucose cotransporter-2 inhibitors (SGLT2is) do not appear to increase the risk of acute kidney injury (AKI), according to the findings of a recently published systematic review and meta-analysis. To evaluate the risk of AKI with these agents, study authors reviewed literature analyzing the effect of SGLT2is on renal adverse events compared with placebo or other…
Preoperative ARB Use May Increase AKI Risk After Surgery
Adult patients who used angiotensin receptor blockers prior to surgery had significant 30% increased odds of acute kidney injury, an Icelandic study found.
Sepsis, Volume Overload Commonly Prompt CRRT
In a study, 43.8% of hospitalized patients had sepsis and 48.8% had fluid overload requiring continuous renal replacement therapy.
Kidney Recovery Predictors in Dialysis-Requiring AKI Identified
Younger age, female sex, and lower serum creatinine are among the variables most strongly associated with recovery of kidney function following initiation of outpatient hemodialysis for acute kidney injury, a study found.
Anemia Predicts Adverse Kidney Events in ICU, Cardiac Surgery Patients
Low hemoglobin levels prior to cardiac surgery or admission to an intensive care unit increases the risk of major adverse kidney events within 7 days, a study found.
Immune Checkpoint Inhibitors May Increase Risk of Acute Kidney Injury
In a real-world study, 3% of AKI events potentially related to use of immune checkpoint inhibitor therapy — a higher rate than reported in clinical trials.
FDA Fast-Tracks Therapy for Patients at Risk for Acute Kidney Injury After CABG/Valve Surgery
The FDA has granted Fast Track designation to ASP1128, an investigational treatment for patients at increased risk of developing moderate to severe acute kidney injury (AKI) after coronary artery bypass and/or valve (CABG/V) surgery.
CHEST: Blood Transfusion Practices Should Be Revisited
Study looks at transfusion practices of intensive care providers in a typical tertiary hospital
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