In a study comparing the effect of 9 oral nonsteroidal anti-inflammatory drugs on kidney function, ibuprofen conferred the lowest risk for incident eGFR less than 60 mL/min/1.73 m2 and an eGFR decline of 30% or greater.
The association of pulmonary hypertension with an increased risk for kidney failure in older adults with chronic kidney disease is a novel finding.
In a small study, 25% of adults with COVID-19 shed SARS-CoV-2 spike S1 protein in their urine at least once during the course of infection.
AKI seen in 14% of patients treated with antibiotic-loaded bone cement spacer after resection of periprosthetic joint infection
Learning how SARS-CoV-2 causes acute kidney injury could improve understanding of kidney physiology.
In a study of Black patients with COVID-19, those with 2 APOL1 risk alleles have increased odds of acute kidney injury.
Nearly two-thirds of hospitalized patients with COVID-19 and acute kidney injury requiring dialysis died during their hospital stay, a study found.
Investigators have developed a rodent model to explore changes in renal function early in pregnancy that predict problems such as preeclampsia, low infant birth weight, and miscarriage.
Understanding kidney sequelae in infected patients with AKI has important public health implications for resource allocation, screening, and patient counseling, according to the investigators.
Avoiding inappropriate use and overdosing of drugs with nephrotoxic effects is an important strategy to prevent hospital-acquired AKI in children, according to investigators.