In a study comparing the effect of 9 oral nonsteroidal anti-inflammatory drugs on kidney function, ibuprofen conferred the lowest risk for incident eGFR less than 60 mL/min/1.73 m2 and an eGFR decline of 30% or greater.
Investigators have developed a rodent model to explore changes in renal function early in pregnancy that predict problems such as preeclampsia, low infant birth weight, and miscarriage.
Understanding kidney sequelae in infected patients with AKI has important public health implications for resource allocation, screening, and patient counseling, according to the investigators.
Avoiding inappropriate use and overdosing of drugs with nephrotoxic effects is an important strategy to prevent hospital-acquired AKI in children, according to investigators.
