FDA Rejects Terlipressin NDA for Hepatorenal Syndrome Type 1
In July 2020, the FDA Cardiovascular and Renal Drugs Advisory Committee narrowly voted 8 to 7 in favor of the approval of terlipressin for HRS-1.
Nephrology
NEPHROLOGY
Venous pH May Inform Treatment of CKD-Related Metabolic Acidosis
In patients with acidemia, hypobicarbonatemia conferred a considerable risk of kidney failure requiring renal replacement therapy after adjusting for potential confounders.
Updated CKD Nutrition Guideline Released
The newest KDOQI guideline for renal nutrition, which took 5 years to develop, expands recommendations to include patients with all stages of chronic kidney disease.
Moderate/High Risk for ESRD Tied to Worse Cognition Later in Life
Those with higher-risk episodes for ESRD as young adults had poorer cognitive performance at midlife.
Simplified Creatinine Index Useful as Muscle Mass Marker in HD Settings
A simplified creatinine index reflects the creatinine generation rate of individual patients on hemodialysis.
Dapagliflozin Reduces Kidney Failure Risk, Prolongs Survival in CKD
Dapagliflozin appears to preserve kidney function and improve survival in patients with chronic kidney disease whether or not they have type 2 diabetes.
Hyponatremia in COVID-19 Cases Ups In-Hospital Mortality
Each level of worsening hyponatremia among patients hospitalized with COVID-19 was significantly associated with 43% increased odds of dying in the hospital, a study found.
Many Opt for Genetic Testing of Embryos for Kidney Disease
65% of couples using IVF who selected testing had at least one live birth of an unaffected child.
Empagliflozin Beneficial in Heart Failure With Reduced Ejection Fraction
In a trial, empagliflozin reduced the risks for heart failure hospitalization and renal outcomes in patients with heart failure with reduced ejection fraction.
CPR Preferences Explored for Patients Receiving Dialysis
Survey shows 23.2% of those who want CPR in the event of cardiac arrest value life prolongation.
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