New-onset hyponatremia is common following surgery for hip fractures, according to British researchers.

James Edward Rudge, MB, and Daniel Kim, MB, of City Hospital, Sandwell and West Birmingham Hospitals NHS Trust – Postgraduate Centre, Birmingham, UK, retrospectively studied 254 patients who underwent hip surgery in 2012. 

The incidence of moderate (less than 135 mmol/L) and severe (less than 130 mmol/L) post-operative hyponatremia was 27% and 9%, respectively, the researchers reported online ahead of print in Age and Ageing.

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Patients with moderate hyponatremia had a significantly longer hospital stay than normonatremic patients (30 vs. 21 days).  Post-operative hyponatremia also was significantly associated with proton pump inhibitor use, selective serotonin re-uptake inhibitor use, and increasing number of medications.