ORLANDO—Patients who initiate renal replacement therapy on peritoneal dialysis (PD) are about 50% less likely to die within 90 days than those who start on hemodialysis (HD), a study found.


Among patients with at least one co-morbidity, those starting on PD have an approximately 25% lower mortality risk than those starting on HD.

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A team at the Chronic Disease Research Group in Minneapolis studied 799,187 patients who initiated therapy in the United States between 1995 and 2004. Among non-diabetics without comorbid conditions at baseline, PD patients were at 56% lower risk of death within the first 90 days than HD patients, after adjusting for gender, age, race, BMI, baseline estimated glomerular filtration rate, hemoglobin, serum albumin, and other factors.


Among non-diabetics with one or more comorbid conditions, PD patients were at 27% lower risk. In the diabetic population, PD patients had a 51% lower mortality risk than HD patients if they had no other comorbidities and a 25% lower risk if they had one or more additional comorbidities. The researchers reported their findings here at the National Kidney Foundation 2007 Spring Clinical Meetings.