Periodontal disease is independently associated with CKD, a study found.


Monica A. Fisher, PhD, DDS, MPH, of Case Western Reserve University in Cleveland, and her colleagues studied 12,947 adults who participated in the Third Health and Nutrition Examination Survey, which looked at a large nationally representative sample of the U.S. population. Subjects had information about kidney function and at least one risk factor for CKD.

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The prevalence of CKD—defined as a glomerular filtration rate of 15-59 mL/min per 1.73 m2—was 3.6%, according to a report in the American Journal of Kidney Diseases (2008;51:45-52). The prevalence of periodontal disease and its severe consequence, edentulism, was 6.0% and 10.5%, respectively.


After adjusting for other traditional and nontraditional risk factors, individuals with periodontal disease and those without teeth were twice as likely as other subjects to have CKD.