NEWS

Diabetic Nephropathy

Finerenone Gets Priority Review for Diabetic Kidney Disease

Publish Date January 18, 2021

The FDA has accepted for Priority Review the NDA for finerenone for chronic kidney disease in patients with type 2 diabetes.

Chronic Kidney Disease (CKD)

Sparsentan Granted Orphan Drug Status for IgA Nephropathy

Publish Date January 18, 2021

Sparsentan is an investigational small molecule candidate designed to selectively block the receptors of endothelin type A and angiotensin II type I, which are associated with kidney disease progression.

Hypertension

Lymphatic Reserve in HFpEF

Publish Date January 18, 2021

Peripheral lymphatic vessels may not compensate for interstitial accumulation and fluid extravasation in HFpEF.

Diabetes

Intensive Glycemic Control May Cut CV Autonomic Neuropathy Risk

Publish Date January 15, 2021

Greatest CAN prevention effect seen among type 2 diabetes patients without cardiovascular disease history.

Chronic Kidney Disease (CKD)

Corticosteroids-Cyclophosphamide May Be Superior for Primary MN

Publish Date January 15, 2021

In a trial of patients with primary membranous nephropathy, corticosteroid-cyclophosphamide induced significantly more and faster remission of nephrotic syndrome than tacrolimus-rituximab.

Lupus Nephritis

Severe Renal Arteriosclerosis in Lupus Nephritis Predicts ASCVD

Publish Date January 15, 2021

Severe renal arteriosclerosis in diagnostic lupus nephritis biopsies is associated with 9-fold higher odds of atherosclerotic cardiovascular disease.

Prostate Cancer

Higher Coffee Intake May Reduce Risk for Prostate Cancer

Publish Date January 15, 2021

Pooled relative risk of 0.988 for each increment of one cup of coffee per day revealed in meta-analysis of cohort studies

Hyperuricemia

Patient Perspectives Valuable to Development of 2020 ACR Gout Treatment Guideline

Publish Date December 21, 2020

Study authors evaluated patient perspectives to inform the voting process for the 2020 American College of Rheumatology gout treatment guideline.

Hemodialysis

Many Dialysis Patients Report Proficiency in Mobile Health

Publish Date January 15, 2021

Older patients have lower mobile health proficiency, as do those with Hispanic/Latinx ethnicity, less than college education

Cardiovascular Disease (CVD)

Cardiac Risk Assessment Low After Noncardiac Surgery

Publish Date January 14, 2021

6.8% of those undergoing noncardiac surgery from January 2013 to December 2017 had preoperative natriuretic peptide screening