Sugar-sweetened beverage (SSB) intake is associated with low serum testosterone levels among men aged 20–39 years in the United States, according to investigators.

In a study of 545 men in this age group who participated in the 2011–2012 National Health and Nutrition Examination Survey, those in the top quartile of SSB intake (442 kcal/day or more) had significant 2.3-fold increased odds of having low testosterone (levels below 231 ng/dL) compared with those in the bottom quartile (137 kcal/day or less) after adjusting for multiple variables.

Results also showed that body mass index (BMI) was an independent risk factor for low testosterone. Men with a BMI of 25 kg/m2 or higher had significant 3.7-fold increased odds of low testosterone compared with those who had a BMI below 25 kg/m2, according to Liang Chen and colleagues from the Guangdong General Hospital, Guangdong Academy of Medical Sciences in Guangzhou, China.

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“The effects of SSB consumption on testosterone levels in adult males must be considered if primary and secondary hypogonadism have been ruled out as a source of low testosterone and related symptoms,” the investigators concluded in Reproductive Biology and Endocrinology (2018;16:61).

The study cohort had a mean age of 28.9 years. Of the 545 participants, 59 (9.6%) had low testosterone.


Chen L, Xie YM, Pei JH, et al. Sugar-sweetened beverage intake and serum testosterone levels in adult males 20–39 years old in the United States. Reprod Biol Endocrinol. 2018;16:61.