Beneficial effects for postmenopausal women, with preference for nonoral testosterone administration
Increased risk in men on TRT for composite of heart attack, ischemic stroke, transient ischemic attack
The increased opioid use has been associated with a rising incidence of opioid-induced endocrinopathy, most commonly in the form of androgen deficiency.
Long-term treatment with testosterone undecanoate was associated with reduced cardiovascular morbidity and mortality in patients with hypogonadism and type 2 diabetes.
Selective estrogen receptor modulators (SERMs) may be effective for treating male infertility, according to a recent systematic review and meta-analysis published in Expert Opinion on Pharmacotherapy. SERMs are compounds that exhibit tissue-selective estrogen receptor agonist and antagonist activity. Clomiphene citrate and tamoxifen are two agents commonly used for the off-label management of male infertility. To…
New studies find no increase in biochemical recurrence risk following radical prostatectomy or radiation therapy associated with testosterone replacement therapy.
A study of American men showed that those who adhered to a low-fat diet were twice as likely as men consuming usual diets to have hypogonadism.
In a small study of radical cystectomy patients, perioperative hypogonadism persisted up to 90 days after surgery.
Genetically low 25-hydroxyvitamin D levels are associated with lower testosterone levels.
In a subanalysis, researchers discovered that testosterone deficiency was common in men with a sustained virologic response after being treated for hepatitis C.