Study reveals an approximately 2-fold increased odds of venous thromboembolism associated with testosterone therapy in men with or without hypogonadism
Rates of screening, treatment for low testosterone higher for prolonged versus short-term opioid users
In a study, investigators observed a reduced probability of prostate cancer in nondiabetic men with greater use of testosterone therapy.
Testosterone only recommended for postmenopausal women with hypoactive sexual desire dysfunction
A study of former US professional football players found that the risk of self-reported indicators of low testosterone and erectile dysfunction increased with each successive quartile of concussion symptom score.
Beneficial effects for postmenopausal women, with preference for nonoral testosterone administration
Increased risk in men on TRT for composite of heart attack, ischemic stroke, transient ischemic attack
The increased opioid use has been associated with a rising incidence of opioid-induced endocrinopathy, most commonly in the form of androgen deficiency.
Long-term treatment with testosterone undecanoate was associated with reduced cardiovascular morbidity and mortality in patients with hypogonadism and type 2 diabetes.
Selective estrogen receptor modulators (SERMs) may be effective for treating male infertility, according to a recent systematic review and meta-analysis published in Expert Opinion on Pharmacotherapy. SERMs are compounds that exhibit tissue-selective estrogen receptor agonist and antagonist activity. Clomiphene citrate and tamoxifen are two agents commonly used for the off-label management of male infertility. To…