Upfront metastasis-directed therapy may be a viable treatment approach in patients with oligorecurrent disease, particularly those who wish to defer systemic therapy.
Patients with localized prostate cancer characterized by high-risk features are at increased risk of a negative outcome following radical prostatectomy.
Men in the highest tertile of high-sensitivity C-reactive protein level had a 30% increased risk for prostate cancer compared with those in the lowest tertile in adjusted analyses.
The trial, which is the first to be implemented under Operation Warp Speed, is expected to enroll around 30,000 adults and will be conducted at multiple clinical research sites across the US.
A large study of patients hospitalized with COVID-19 found that treatment with hydroxychloroquine alone or with azithromycin decreased the risk of in-hospital death by 66% and 71%, respectively, compared with not receiving either treatment.
