VANCOUVER, B.C.—Greater fish consumption is associated with smaller declines in kidney function in women, researchers reported at the World Congress of Nephrology.

Julie Lin, MD, MPH, FASN, and colleagues at Brigham and Women’s Hospital in Boston analyzed data from 3,318 women participating in the Nurses’ Health Study who had data available on diet and albuminuria. Of these, 3,256 also had information on changes in estimated glomerular filtration rate (eGFR) between 1989 and 2000. The study population included 730 women with diabetes participating in a sub-study of renal function. The study cohort had a median age of 67 years and 97% were Caucasian.

Compared with women who ate less than one serving of fish per week, those who consumed two or more servings per week had a 29% decreased risk for a faster decline (defined as a 30% or greater decrease over 11 years) in eGFR after adjustment for multiple variables, including age, hypertension, body mass index, diabetes, cigarette smoking, physical activity, cardiovascular disease, and other dietary factors.

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Twenty-eight percent of the cohort consumed less than one serving of fish per week, 41% consumed 1-1.9 servings per week, and 31% consumed two or more servings per week.

The investigators observed no association between fish consumption and microalbuminuria.